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Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis

BACKGROUND: To compare the difference in central corneal thickness (CCT) measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer (Sirius, CSO, Italy) and ultrasound pachymetry (USP). METHODS: A systematic literature search was conducted for...

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Autores principales: Jin, Yili, McAlinden, Colm, Sun, Yong, Wen, Daizong, Wang, Yiran, Yu, Jinjin, Feng, Ke, Song, Benhao, Wang, Qinmei, Chen, Shihao, Huang, Jinhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891160/
https://www.ncbi.nlm.nih.gov/pubmed/33602345
http://dx.doi.org/10.1186/s40662-021-00227-5
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author Jin, Yili
McAlinden, Colm
Sun, Yong
Wen, Daizong
Wang, Yiran
Yu, Jinjin
Feng, Ke
Song, Benhao
Wang, Qinmei
Chen, Shihao
Huang, Jinhai
author_facet Jin, Yili
McAlinden, Colm
Sun, Yong
Wen, Daizong
Wang, Yiran
Yu, Jinjin
Feng, Ke
Song, Benhao
Wang, Qinmei
Chen, Shihao
Huang, Jinhai
author_sort Jin, Yili
collection PubMed
description BACKGROUND: To compare the difference in central corneal thickness (CCT) measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer (Sirius, CSO, Italy) and ultrasound pachymetry (USP). METHODS: A systematic literature search was conducted for relevant studies published on PubMed, Medline, EMBASE, and the Cochrane Library and ClinicalTrials.gov from inception to August 1st, 2019. Primary outcome measures were CCT measurements between Sirius and USP. A random effects model was used to pool CCT measurements. RESULTS: A total of twelve studies involving 862 eyes were included in this meta-analysis. The meta-analysis found CCT measurements between Sirius and USP to be statistically significantly different (P < 0.0001). The mean difference between Sirius and USP was −11.26 μm with a 95% confidence interval (CI) (−16.92 μm, −5.60 μm). The heterogeneity was I(2) = 60% (P = 0.004). CONCLUSION: CCT measurements with the Sirius Scheimpflug-Placido topographer were statistically significantly lower than USP. However, it may be argued that the mean difference of 11.26 μm is not a clinically significant difference.
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spelling pubmed-78911602021-02-22 Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis Jin, Yili McAlinden, Colm Sun, Yong Wen, Daizong Wang, Yiran Yu, Jinjin Feng, Ke Song, Benhao Wang, Qinmei Chen, Shihao Huang, Jinhai Eye Vis (Lond) Research BACKGROUND: To compare the difference in central corneal thickness (CCT) measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer (Sirius, CSO, Italy) and ultrasound pachymetry (USP). METHODS: A systematic literature search was conducted for relevant studies published on PubMed, Medline, EMBASE, and the Cochrane Library and ClinicalTrials.gov from inception to August 1st, 2019. Primary outcome measures were CCT measurements between Sirius and USP. A random effects model was used to pool CCT measurements. RESULTS: A total of twelve studies involving 862 eyes were included in this meta-analysis. The meta-analysis found CCT measurements between Sirius and USP to be statistically significantly different (P < 0.0001). The mean difference between Sirius and USP was −11.26 μm with a 95% confidence interval (CI) (−16.92 μm, −5.60 μm). The heterogeneity was I(2) = 60% (P = 0.004). CONCLUSION: CCT measurements with the Sirius Scheimpflug-Placido topographer were statistically significantly lower than USP. However, it may be argued that the mean difference of 11.26 μm is not a clinically significant difference. BioMed Central 2021-02-18 /pmc/articles/PMC7891160/ /pubmed/33602345 http://dx.doi.org/10.1186/s40662-021-00227-5 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Jin, Yili
McAlinden, Colm
Sun, Yong
Wen, Daizong
Wang, Yiran
Yu, Jinjin
Feng, Ke
Song, Benhao
Wang, Qinmei
Chen, Shihao
Huang, Jinhai
Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
title Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
title_full Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
title_fullStr Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
title_full_unstemmed Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
title_short Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
title_sort sirius scheimpflug–placido versus ultrasound pachymetry for central corneal thickness: meta-analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891160/
https://www.ncbi.nlm.nih.gov/pubmed/33602345
http://dx.doi.org/10.1186/s40662-021-00227-5
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