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Rationale and Design of the Genotype-Blinded Trial of Torasemide for the Treatment of Hypertension (BHF UMOD)

BACKGROUND: Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) near the uromodulin gene (UMOD) affecting uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb (TAL) of the loop of Henle and its effect...

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Detalles Bibliográficos
Autores principales:	McCallum, Linsay, Brooksbank, Katriona, McConnachie, Alex, Aman, Alisha, Lip, Stefanie, Dawson, Jesse, MacIntyre, Iain M, MacDonald, Thomas M, Webb, David J, Padmanabhan, Sandosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891239/ https://www.ncbi.nlm.nih.gov/pubmed/33084880 http://dx.doi.org/10.1093/ajh/hpaa166

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