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Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy
PURPOSE: To investigate the long‐term outcomes of patients who underwent vitrectomy for proliferative diabetic retinopathy. METHODS: Cumulative incidences were calculated for low vision (<0.3), re‐vitrectomy in the study eye and fellow eye vitrectomy. To identify potential prognostic factors that...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891313/ https://www.ncbi.nlm.nih.gov/pubmed/32643273 http://dx.doi.org/10.1111/aos.14482 |
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author | Schreur, Vivian Brouwers, Jody Van Huet, Ramon A.C. Smeets, Sandra Phan, Milan Hoyng, Carel B. de Jong, Eiko K. Klevering, B. Jeroen |
author_facet | Schreur, Vivian Brouwers, Jody Van Huet, Ramon A.C. Smeets, Sandra Phan, Milan Hoyng, Carel B. de Jong, Eiko K. Klevering, B. Jeroen |
author_sort | Schreur, Vivian |
collection | PubMed |
description | PURPOSE: To investigate the long‐term outcomes of patients who underwent vitrectomy for proliferative diabetic retinopathy. METHODS: Cumulative incidences were calculated for low vision (<0.3), re‐vitrectomy in the study eye and fellow eye vitrectomy. To identify potential prognostic factors that associate with these outcomes, we used multivariable Cox regression models. RESULTS: In a total of 217 patients, we found 1‐, 5‐ and 10‐year cumulative incidences of low vision in the study eye of 24%, 31% and 39%, respectively. For both eyes, these rates were, respectively, 10%, 14% and 14%. Low vision in both eyes was associated with higher age and worse contralateral visual acuity. The 1‐, 5‐ and 10‐year cumulative incidences for re‐vitrectomy in the study eye were 16%, 27% and 27%, respectively, and for a vitrectomy in the fellow eye 24%, 40% and 54%, respectively. Re‐vitrectomy of the study eye was associated with worse contralateral visual acuity, while vitrectomy of the fellow eye was associated with shorter diabetes duration, worse contralateral visual acuity, higher HbA1c level and worse diabetic retinopathy severity stage of the fellow eye. CONCLUSION: Functional visual acuity in at least one eye was achieved or preserved in most patients. After 10 years, about a quarter of all patients underwent a re‐vitrectomy, while more than half of the patients needed a vitrectomy of the fellow eye. Knowledge of these long‐term outcomes is essential when counselling patients for a vitrectomy. |
format | Online Article Text |
id | pubmed-7891313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78913132021-03-02 Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy Schreur, Vivian Brouwers, Jody Van Huet, Ramon A.C. Smeets, Sandra Phan, Milan Hoyng, Carel B. de Jong, Eiko K. Klevering, B. Jeroen Acta Ophthalmol Original Articles PURPOSE: To investigate the long‐term outcomes of patients who underwent vitrectomy for proliferative diabetic retinopathy. METHODS: Cumulative incidences were calculated for low vision (<0.3), re‐vitrectomy in the study eye and fellow eye vitrectomy. To identify potential prognostic factors that associate with these outcomes, we used multivariable Cox regression models. RESULTS: In a total of 217 patients, we found 1‐, 5‐ and 10‐year cumulative incidences of low vision in the study eye of 24%, 31% and 39%, respectively. For both eyes, these rates were, respectively, 10%, 14% and 14%. Low vision in both eyes was associated with higher age and worse contralateral visual acuity. The 1‐, 5‐ and 10‐year cumulative incidences for re‐vitrectomy in the study eye were 16%, 27% and 27%, respectively, and for a vitrectomy in the fellow eye 24%, 40% and 54%, respectively. Re‐vitrectomy of the study eye was associated with worse contralateral visual acuity, while vitrectomy of the fellow eye was associated with shorter diabetes duration, worse contralateral visual acuity, higher HbA1c level and worse diabetic retinopathy severity stage of the fellow eye. CONCLUSION: Functional visual acuity in at least one eye was achieved or preserved in most patients. After 10 years, about a quarter of all patients underwent a re‐vitrectomy, while more than half of the patients needed a vitrectomy of the fellow eye. Knowledge of these long‐term outcomes is essential when counselling patients for a vitrectomy. John Wiley and Sons Inc. 2020-07-09 2021-02 /pmc/articles/PMC7891313/ /pubmed/32643273 http://dx.doi.org/10.1111/aos.14482 Text en © 2020 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Schreur, Vivian Brouwers, Jody Van Huet, Ramon A.C. Smeets, Sandra Phan, Milan Hoyng, Carel B. de Jong, Eiko K. Klevering, B. Jeroen Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
title | Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
title_full | Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
title_fullStr | Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
title_full_unstemmed | Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
title_short | Long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
title_sort | long‐term outcomes of vitrectomy for proliferative diabetic retinopathy |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891313/ https://www.ncbi.nlm.nih.gov/pubmed/32643273 http://dx.doi.org/10.1111/aos.14482 |
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