Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli

TLR‐inducible zinc toxicity is an antimicrobial mechanism utilized by macrophages, however knowledge of molecular mechanisms mediating this response is limited. Here, we show that E. coli exposed to zinc stress within primary human macrophages reside in membrane‐bound vesicular compartments. Since S...

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Detalles Bibliográficos
Autores principales: Stocks, Claudia J., von Pein, Jessica B., Curson, James E.B., Rae, James, Phan, Minh‐Duy, Foo, Darren, Bokil, Nilesh J., Kambe, Taiho, Peters, Kate M., Parton, Robert G., Schembri, Mark A., Kapetanovic, Ronan, Sweet, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Spotlight on Leading Edge Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891337/
https://www.ncbi.nlm.nih.gov/pubmed/32441444
http://dx.doi.org/10.1002/JLB.2HI0420-160R

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