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Blinded, Double‐Dummy, Parallel‐Group, Phase 2a Randomized Clinical Trial to Evaluate the Efficacy and Safety of a Highly Selective 5‐Hydroxytryptamine Type 4 Receptor Agonist in Critically Ill Patients With Enteral Feeding Intolerance

BACKGROUND: Delayed gastric emptying is the leading cause of enteral feeding intolerance (EFI) in critical illness. This phase 2a study compared TAK‐954, a selective agonist of 5‐hydroxytryptamine type 4 receptors, with metoclopramide in critically ill patients with EFI (NCT01953081). METHODS: A bli...

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Detalles Bibliográficos
Autores principales:	Chapman, Marianne J., Jones, Karen L., Almansa, Cristina, Barnes, Chris N., Nguyen, Deanna, Deane, Adam M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891369/ https://www.ncbi.nlm.nih.gov/pubmed/31990087 http://dx.doi.org/10.1002/jpen.1732

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