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Unfolded protein response activation in C9orf72 frontotemporal dementia is associated with dipeptide pathology and granulovacuolar degeneration in granule cells

A repeat expansion in the C9orf72 gene is the most prevalent genetic cause of frontotemporal dementia (C9‐FTD). Several studies have indicated the involvement of the unfolded protein response (UPR) in C9‐FTD. In human neuropathology, UPR markers are strongly associated with granulovacuolar degenerat...

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Detalles Bibliográficos
Autores principales:	Gami‐Patel, Priya, van Dijken, Irene, Meeter, Lieke H., Melhem, Shamiram, Morrema, Tjado H. J., Scheper, Wiep, van Swieten, John C., Rozemuller, Annemieke J. M., Dijkstra, Anke A., Hoozemans, Jeroen J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891436/ https://www.ncbi.nlm.nih.gov/pubmed/32865835 http://dx.doi.org/10.1111/bpa.12894

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