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Chromatin regulators in retinoblastoma: Biological roles and therapeutic applications

Retinoblastoma (RB) is a pediatric ocular tumor mostly occurring due to the biallelic loss of RB1 gene in the developing retina. Early studies of genomic aberrations in RB have provided a valuable insight into how RB can progress following the tumor‐initiating RB1 mutations and have established a no...

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Detalles Bibliográficos
Autores principales: Lee, Chunsik, Kim, Jong Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891620/
https://www.ncbi.nlm.nih.gov/pubmed/32840881
http://dx.doi.org/10.1002/jcp.30022