Cargando…
Loci identified by a genome‐wide association study of carotid artery stenosis in the eMERGE network
Carotid artery atherosclerotic disease (CAAD) is a risk factor for stroke. We used a genome‐wide association (GWAS) approach to discover genetic variants associated with CAAD in participants in the electronic Medical Records and Genomics (eMERGE) Network. We identified adult CAAD cases with unilater...
Autores principales: | Palmer, Melody R., Kim, Daniel S., Crosslin, David R., Stanaway, Ian B., Rosenthal, Elisabeth A., Carrell, David S., Cronkite, David J., Gordon, Adam, Du, Xiaomeng, Li, Yatong K., Williams, Marc S., Weng, Chunhua, Feng, Qiping, Li, Rongling, Pendergrass, Sarah A., Hakonarson, Hakon, Fasel, David, Sohn, Sunghwan, Sleiman, Patrick, Handelman, Samuel K., Speliotes, Elizabeth, Kullo, Iftikhar J., Larson, Eric B., Jarvik, Gail P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891640/ https://www.ncbi.nlm.nih.gov/pubmed/32964493 http://dx.doi.org/10.1002/gepi.22360 |
Ejemplares similares
-
Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and
multivariate methods on 43,870 individuals from the eMERGE network
por: Zhang, Xinyuan, et al.
Publicado: (2019) -
Evaluation of the MC4R gene across eMERGE network identifies many unreported obesity-associated variants
por: Namjou, Bahram, et al.
Publicado: (2020) -
The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype
por: Stanaway, Ian B., et al.
Publicado: (2018) -
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network
por: Namjou, Bahram, et al.
Publicado: (2019) -
eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants
por: Verma, Anurag, et al.
Publicado: (2016)