An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes

The appropriate regulation of T lymphocyte functions is key to achieve protective immune responses, while at the same time limiting the risks of tissue damage and chronic inflammation. Deciphering the mechanisms underpinning T cell responses in humans may therefore be beneficial for a range of infec...

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Detalles Bibliográficos
Autores principales: Leoni, Cristina, Bianchi, Niccolò, Vincenzetti, Lucia, Monticelli, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891767/
https://www.ncbi.nlm.nih.gov/pubmed/33600503
http://dx.doi.org/10.1371/journal.pone.0247232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891767/
https://www.ncbi.nlm.nih.gov/pubmed/33600503
http://dx.doi.org/10.1371/journal.pone.0247232

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