Cargando…
An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes
The appropriate regulation of T lymphocyte functions is key to achieve protective immune responses, while at the same time limiting the risks of tissue damage and chronic inflammation. Deciphering the mechanisms underpinning T cell responses in humans may therefore be beneficial for a range of infec...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891767/ https://www.ncbi.nlm.nih.gov/pubmed/33600503 http://dx.doi.org/10.1371/journal.pone.0247232 |