Hydrogen sulfide inhibits endoplasmic reticulum stress through the GRP78/mTOR pathway in rat chondrocytes subjected to oxidative stress

The activation of oxidative stress is a primary cause of chondrocyte apoptosis in osteoarthritis (OA). The 78-kDa glucose-regulated protein (GRP78)/mammalian target of rapamycin (mTOR) signaling pathway has been demonstrated to be linked with the endoplasmic reticulum (ER) and autophagy. Hydrogen su...

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Detalles Bibliográficos
Autores principales: Wu, Jianjun, Yang, Fan, Zhang, Xin, Chen, Guanghua, Zou, Jilong, Yin, Li, Yang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891823/
https://www.ncbi.nlm.nih.gov/pubmed/33537813
http://dx.doi.org/10.3892/ijmm.2021.4867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891823/
https://www.ncbi.nlm.nih.gov/pubmed/33537813
http://dx.doi.org/10.3892/ijmm.2021.4867

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