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The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types

A novel variant of the SARS-CoV-2 virus carrying a point mutation in the Spike protein (D614G) has recently emerged and rapidly surpassed others in prevalence. This mutation is in linkage disequilibrium with an ORF1b protein variant (P314L), making it difficult to discern the functional significance...

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Detalles Bibliográficos
Autores principales:	Daniloski, Zharko, Jordan, Tristan X, Ilmain, Juliana K, Guo, Xinyi, Bhabha, Gira, tenOever, Benjamin R, Sanjana, Neville E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Epidemiology and Global Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7891930/ https://www.ncbi.nlm.nih.gov/pubmed/33570490 http://dx.doi.org/10.7554/eLife.65365

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