iTRAQ-Based Quantitative Proteomics Indicated Nrf2/OPTN-Mediated Mitophagy Inhibits NLRP3 Inflammasome Activation after Intracerebral Hemorrhage

Intracerebral hemorrhage- (ICH-) induced secondary brain injury (SBI) is a very complex pathophysiological process. However, the molecular mechanisms and drug targets of SBI are highly intricate and still elusive, yet a clear understanding is crucial for the treatment of SBI. In the current study, w...

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Detalles Bibliográficos
Autores principales: Cheng, Yijun, Liu, Mingjian, Tang, Hao, Chen, Bin, Yang, Guoyuan, Zhao, Weiguo, Cai, Yu, Shang, Hanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892225/
https://www.ncbi.nlm.nih.gov/pubmed/33628368
http://dx.doi.org/10.1155/2021/6630281

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