Identification of high affinity and low molecular alternatives of boceprevir against SARS-CoV-2 main protease: A virtual screening approach

SARS-CoV-2 has posed global challenge for healthcare due to COVID-19. The main protease (M(pro)) of this virus is considered as a major target for drug development efforts. In this work, we have used virtual screening approach with molecular dynamics simulations to identify high affinity and low mol...

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Detalles Bibliográficos
Autores principales: Borkotoky, Subhomoi, Banerjee, Manidipa, Modi, Gyan Prakash, Dubey, Vikash Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892318/
https://www.ncbi.nlm.nih.gov/pubmed/33623170
http://dx.doi.org/10.1016/j.cplett.2021.138446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892318/
https://www.ncbi.nlm.nih.gov/pubmed/33623170
http://dx.doi.org/10.1016/j.cplett.2021.138446

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