Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms

OBJECTIVES: Juvenile idiopathic arthritis (JIA) is the most prevalent form of juvenile rheumatic disease. Our understanding of the genetic risk factors for this disease is limited due to low disease prevalence and extensive clinical heterogeneity. The objective of this research is to identify novel...

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Detalles Bibliográficos
Autores principales: López-Isac, Elena, Smith, Samantha L, Marion, Miranda C, Wood, Abigail, Sudman, Marc, Yarwood, Annie, Shi, Chenfu, Gaddi, Vasanthi Priyadarshini, Martin, Paul, Prahalad, Sampath, Eyre, Stephen, Orozco, Gisela, Morris, Andrew P, Langefeld, Carl D, Thompson, Susan D, Thomson, Wendy, Bowes, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Paediatric Rheumatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892389/
https://www.ncbi.nlm.nih.gov/pubmed/33106285
http://dx.doi.org/10.1136/annrheumdis-2020-218481

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