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Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis

Toxoplasma gondii is a neurotropic protozoan parasite, which is linked to neurological manifestations in immunocompromised individuals as well as severe neurodevelopmental sequelae in congenital toxoplasmosis. While the complement system is the first line of host defense that plays a significant rol...

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Detalles Bibliográficos
Autores principales:	Shinjyo, Noriko, Hikosaka, Kenji, Kido, Yasutoshi, Yoshida, Hiroki, Norose, Kazumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892429/ https://www.ncbi.nlm.nih.gov/pubmed/33613523 http://dx.doi.org/10.3389/fimmu.2020.603924

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