Bronchoalveolar Lavage Fluid Reflects a T(H)1-CD21(low) B-Cell Interaction in CVID-Related Interstitial Lung Disease

BACKGROUND: About 20% of patients with common variable immunodeficiency (CVID) suffer from interstitial lung disease (ILD) as part of a systemic immune dysregulation. Current understanding suggests a role of B cells in the pathogenesis based on histology and increased levels of BAFF and IgM associat...

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Detalles Bibliográficos
Autores principales: Friedmann, David, Unger, Susanne, Keller, Baerbel, Rakhmanov, Mirzokhid, Goldacker, Sigune, Zissel, Gernot, Frye, Björn C., Schupp, Jonas C., Prasse, Antje, Warnatz, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892466/
https://www.ncbi.nlm.nih.gov/pubmed/33613543
http://dx.doi.org/10.3389/fimmu.2020.616832

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