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Organoid Models of Glioblastoma and Their Role in Drug Discovery
Glioblastoma (GBM) is a devastating adult brain cancer with high rates of recurrence and treatment resistance. Cellular heterogeneity and extensive invasion of surrounding brain tissues are characteristic features of GBM that contribute to its intractability. Current GBM model systems do not recapit...
Autores principales: | Rybin, Matthew J., Ivan, Michael E., Ayad, Nagi G., Zeier, Zane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892608/ https://www.ncbi.nlm.nih.gov/pubmed/33613198 http://dx.doi.org/10.3389/fncel.2021.605255 |
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