Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Impact of Oncogenetics Depends on Treatment

Robust and applicable risk-stratifying genetic factors at diagnosis in pediatric T-cell acute lymphoblastic leukemia (T-ALL) are still lacking, and most protocols rely on measurable residual disease (MRD) assessment. In our study, we aimed to analyze the impact of NOTCH1, FBXW7, PTEN, and RAS mutati...

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Detalles Bibliográficos
Autores principales: Vega-García, Nerea, Perez-Jaume, Sara, Esperanza-Cebollada, Elena, Vicente-Garcés, Clara, Torrebadell, Montserrat, Jiménez-Velasco, Antonio, Ortega, Margarita, Llop, Marta, Abad, Lorea, Vagace, José Manuel, Minguela, Alfredo, Pratcorona, Marta, Sánchez-Garcia, Joaquín, García-Calderón, Clara B., Gómez-Casares, María Teresa, Martín-Clavero, Estela, Escudero, Adela, Riñón Martinez-Gallo, Marta, Muñoz, Luz, Velasco, María Rosario, García-Morin, Marina, Català, Albert, Pascual, Antonia, Velasco, Pablo, Fernández, José Mª., Lassaletta, Alvaro, Fuster, José Luis, Badell, Isabel, Molinos-Quintana, Águeda, Molinés, Antonio, Guerra-García, Pilar, Pérez-Martínez, Antonio, García-Abós, Miriam, Robles Ortiz, Reyes, Pisa, Sandra, Adán, Rosa, Díaz de Heredia, Cristina, Dapena, José Luis, Rives, Susana, Ramírez-Orellana, Manuel, Camós, Mireia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892614/
https://www.ncbi.nlm.nih.gov/pubmed/33614543
http://dx.doi.org/10.3389/fped.2020.614521

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