Cargando…

An E2F1/DDX11/EZH2 Positive Feedback Loop Promotes Cell Proliferation in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) accounts for one of the leading causes of cancer-related death, and is attributed to the dysregulation of genes involved in genome stability. DDX11, a DNA helicase, has been implicated in rare genetic disease and human cancers. Yet, its clinical value, biological funct...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Shu-Guang, Li, Qiu-Li, Zhang, Mei-Fang, Zhang, Peng-Wei, Shen, Huimin, Zhang, Chris Zhiyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892623/ https://www.ncbi.nlm.nih.gov/pubmed/33614480 http://dx.doi.org/10.3389/fonc.2020.593293

Ejemplares similares

A positive feedback loop of CENPU/E2F6/E2F1 facilitates proliferation and metastasis via ubiquitination of E2F6 in hepatocellular carcinoma
por: Liu, Yingyi, et al.
Publicado: (2022)

A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X
por: Pan, Yuliang, et al.
Publicado: (2022)

DDX11-AS1 as potential therapy targets for human hepatocellular carcinoma
por: Shi, Min, et al.
Publicado: (2017)

A positive feedback loop of CENPU/E2F6/E2F1 facilitates proliferation and metastasis via ubiquitination of E2F6 in hepatocellular carcinoma: Erratum
por: Liu, Yingyi, et al.
Publicado: (2023)

Involvement of aberrantly activated HOTAIR/EZH2/miR-193a feedback loop in progression of prostate cancer
por: Ling, Zhixin, et al.
Publicado: (2017)

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop
por: Béguelin, Wendy, et al.
Publicado: (2017)

Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma
por: Xie, Cheng-Rong, et al.
Publicado: (2015)

A positive feedback loop between EZH2 and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration
por: Liu, Chang, et al.
Publicado: (2020)

EZH2 upregulation by ERα induces proliferation and migration of papillary thyroid carcinoma
por: Xue, Liqiong, et al.
Publicado: (2019)

E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway
por: Yu, Yan, et al.
Publicado: (2020)

The FUS/circEZH2/KLF5/ feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition
por: Liu, Peng, et al.
Publicado: (2022)

HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop
por: Guo, Kaixuan, et al.
Publicado: (2023)

An E2F1/MiR-17-92 Negative Feedback Loop mediates proliferation of Mouse Palatal Mesenchymal Cells
por: Li, Ling, et al.
Publicado: (2017)

EZH2 in hepatocellular carcinoma: progression, immunity, and potential targeting therapies
por: Wang, Bohan, et al.
Publicado: (2023)

The Clinical Value of Long Noncoding RNA DDX11-AS1 as a Biomarker for the Diagnosis and Prognosis of Hepatocellular Carcinoma
por: Luo, Xiaojun, et al.
Publicado: (2022)

Long non‐coding RNA LINC01535 promotes cervical cancer progression via targeting the miR‐214/EZH2 feedback loop
por: Song, Hongjuan, et al.
Publicado: (2019)

The correlation of EZH2 expression with the progression and prognosis of hepatocellular carcinoma
por: Wu, Shi-yi, et al.
Publicado: (2022)

Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2
por: Guo, Jianping, et al.
Publicado: (2018)

Curcumin inhibits proliferation of hepatocellular carcinoma cells by blocking PTPN1 and PTPN11 expression
por: Zhang, Jingru, et al.
Publicado: (2023)

Knockdown of DDX5 Inhibits the Proliferation and Tumorigenesis in Esophageal Cancer
por: Ma, Zhenchuan, et al.
Publicado: (2017)

LncRNA NR-104098 Inhibits AML Proliferation and Induces Differentiation Through Repressing EZH2 Transcription by Interacting With E2F1
por: Feng, Yubin, et al.
Publicado: (2020)

Long non-coding RNA DDX11-AS1 promotes the proliferation and migration of glioma cells by combining with HNRNPC
por: Xiang, Zijin, et al.
Publicado: (2022)

EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy
por: Lui, Julian C., et al.
Publicado: (2016)

E2F1-miR-20a-5p/20b-5p auto-regulatory feedback loop involved in myoblast proliferation and differentiation
por: Luo, Wen, et al.
Publicado: (2016)

EZH2 negatively regulates PD-L1 expression in hepatocellular carcinoma
por: Xiao, Gang, et al.
Publicado: (2019)

Knockdown of ZBTB11 impedes R‐loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer
por: Chen, Lei, et al.
Publicado: (2022)

Associations of DDX60L With the Clinical Features and Prognosis of Hepatocellular Carcinoma
por: Ye, Ziqi, et al.
Publicado: (2022)

EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop
por: Lin, Junhao, et al.
Publicado: (2021)

Silencing of MBD2 and EZH2 inhibits the proliferation of colorectal carcinoma cells by rescuing the expression of SFRP
por: Xie, Yang, et al.
Publicado: (2021)

The miR-532-E2F1 feedback loop contributes to gastric cancer progression
por: Gao, Shanting, et al.
Publicado: (2022)

MicroRNA-424/E2F6 feedback loop modulates cell invasion, migration and EMT in endometrial carcinoma
por: Lu, Zheng, et al.
Publicado: (2017)

FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis
por: Zhang, Peng, et al.
Publicado: (2021)

The role of EZH1 and EZH2 in development and cancer
por: Lee, Soo Hyun, et al.
Publicado: (2022)

Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly
por: Yang, Fenghua, et al.
Publicado: (2023)

THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate
por: Polenkowski, Mareike, et al.
Publicado: (2022)

MiR-32 Inhibits Proliferation and Metastasis by Targeting EZH2 in Glioma
por: Zhang, Yuan, et al.
Publicado: (2019)

FGFR4 and EZH2 inhibitors synergistically induce hepatocellular carcinoma apoptosis via repressing YAP signaling
por: Yang, Yiqi, et al.
Publicado: (2023)

EZH2 Depletion Blocks the Proliferation of Colon Cancer Cells
por: Fussbroich, Bettina, et al.
Publicado: (2011)

EZH2 is highly expressed in pituitary adenomas and associated with proliferation
por: Schult, David, et al.
Publicado: (2015)

Distinct binding pattern of EZH2 and JARID2 on RNAs and DNAs in hepatocellular carcinoma development
por: Wen, Zhili, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h4177pj6jc9sgd7fs7t3utoc2a