Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections

Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and flucon...

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Detalles Bibliográficos
Autores principales: George, James C., Sainulabdeen, Jishar, Chittaranjan, Samuel, George, Koshy, Babu, Subin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892626/
https://www.ncbi.nlm.nih.gov/pubmed/33659600
http://dx.doi.org/10.1016/j.artd.2020.12.014
Descripción
Sumario:Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and fluconazole monotherapy. They remain asymptomatic with good knee society score after 2 years of follow-up. Preoperative workup of all aseptic loosening cases should include extended culture for fungal elements. Single-stage revision with antifungal therapy for 3 months gives good results in nonimmunocompromised patients with good soft-tissue envelope.

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