Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections

Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and flucon...

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Autores principales: George, James C., Sainulabdeen, Jishar, Chittaranjan, Samuel, George, Koshy, Babu, Subin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892626/
https://www.ncbi.nlm.nih.gov/pubmed/33659600
http://dx.doi.org/10.1016/j.artd.2020.12.014
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author George, James C.
Sainulabdeen, Jishar
Chittaranjan, Samuel
George, Koshy
Babu, Subin
author_facet George, James C.
Sainulabdeen, Jishar
Chittaranjan, Samuel
George, Koshy
Babu, Subin
author_sort George, James C.
collection PubMed
description Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and fluconazole monotherapy. They remain asymptomatic with good knee society score after 2 years of follow-up. Preoperative workup of all aseptic loosening cases should include extended culture for fungal elements. Single-stage revision with antifungal therapy for 3 months gives good results in nonimmunocompromised patients with good soft-tissue envelope.
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spelling pubmed-78926262021-03-02 Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections George, James C. Sainulabdeen, Jishar Chittaranjan, Samuel George, Koshy Babu, Subin Arthroplast Today Case Report Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and fluconazole monotherapy. They remain asymptomatic with good knee society score after 2 years of follow-up. Preoperative workup of all aseptic loosening cases should include extended culture for fungal elements. Single-stage revision with antifungal therapy for 3 months gives good results in nonimmunocompromised patients with good soft-tissue envelope. Elsevier 2021-02-11 /pmc/articles/PMC7892626/ /pubmed/33659600 http://dx.doi.org/10.1016/j.artd.2020.12.014 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
George, James C.
Sainulabdeen, Jishar
Chittaranjan, Samuel
George, Koshy
Babu, Subin
Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections
title Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections
title_full Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections
title_fullStr Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections
title_full_unstemmed Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections
title_short Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections
title_sort single-stage revision with fluconazole monotherapy in fungal prosthetic knee joint infections
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892626/
https://www.ncbi.nlm.nih.gov/pubmed/33659600
http://dx.doi.org/10.1016/j.artd.2020.12.014
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