Repurposing mesalazine against cardiac fibrosis in vitro

Cardiovascular diseases are exacerbated and driven by cardiac fibrosis. TGFβ induces fibroblast activation and differentiation into myofibroblasts that secrete excessive extracellular matrix proteins leading to stiffening of the heart, concomitant cardiac dysfunction, and arrhythmias. However, effec...

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Detalles Bibliográficos
Autores principales: Hoffmann, Maximilian, Kant, Theresa A., Emig, Ramona, Rausch, Johanna S. E., Newe, Manja, Schubert, Mario, Künzel, Karolina, Winter, Luise, Klapproth, Erik, Peyronnet, Rémi, Ravens, Ursula, El-Armouche, Ali, Künzel, Stephan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892689/
https://www.ncbi.nlm.nih.gov/pubmed/33064167
http://dx.doi.org/10.1007/s00210-020-01998-9

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