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On the irrationality of rational design of an HIV vaccine in light of protein intrinsic disorder
The lack of progress in finding an efficient vaccine for a human immunodeficiency virus (HIV) is daunting. In fact, this search has spanned nearly four decades without much success. There are several objective reasons for such a failure, which include the highly glycosylated nature of HIV-1, the pre...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Vienna
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892713/ https://www.ncbi.nlm.nih.gov/pubmed/33606110 http://dx.doi.org/10.1007/s00705-021-04984-5 |