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On the irrationality of rational design of an HIV vaccine in light of protein intrinsic disorder

The lack of progress in finding an efficient vaccine for a human immunodeficiency virus (HIV) is daunting. In fact, this search has spanned nearly four decades without much success. There are several objective reasons for such a failure, which include the highly glycosylated nature of HIV-1, the pre...

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Detalles Bibliográficos
Autor principal: Uversky, Vladimir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892713/
https://www.ncbi.nlm.nih.gov/pubmed/33606110
http://dx.doi.org/10.1007/s00705-021-04984-5

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