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Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position

PURPOSE: To share our experiences in implementing a dedicated magnetic resonance (MR) scanner for radiotherapy (RT) treatment planning using a novel coil setup for brain imaging in treatment position as well as to present developed core protocols with sequences specifically tuned for brain and prost...

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Autores principales: Mengling, Veit, Bert, Christoph, Perrin, Rosalind, Masitho, Siti, Weissmann, Thomas, Mansoorian, Sina, Siavooshhaghighi, Hadi, Janka, Rolf, Doussin, Sylvain, Habatsch, Melanie, Fietkau, Rainer, Putz, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892740/
https://www.ncbi.nlm.nih.gov/pubmed/33103231
http://dx.doi.org/10.1007/s00066-020-01703-y
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author Mengling, Veit
Bert, Christoph
Perrin, Rosalind
Masitho, Siti
Weissmann, Thomas
Mansoorian, Sina
Siavooshhaghighi, Hadi
Janka, Rolf
Doussin, Sylvain
Habatsch, Melanie
Fietkau, Rainer
Putz, Florian
author_facet Mengling, Veit
Bert, Christoph
Perrin, Rosalind
Masitho, Siti
Weissmann, Thomas
Mansoorian, Sina
Siavooshhaghighi, Hadi
Janka, Rolf
Doussin, Sylvain
Habatsch, Melanie
Fietkau, Rainer
Putz, Florian
author_sort Mengling, Veit
collection PubMed
description PURPOSE: To share our experiences in implementing a dedicated magnetic resonance (MR) scanner for radiotherapy (RT) treatment planning using a novel coil setup for brain imaging in treatment position as well as to present developed core protocols with sequences specifically tuned for brain and prostate RT treatment planning. MATERIALS AND METHODS: Our novel setup consists of two large 18-channel flexible coils and a specifically designed wooden mask holder mounted on a flat tabletop overlay, which allows patients to be measured in treatment position with mask immobilization. The signal-to-noise ratio (SNR) of this setup was compared to the vendor-provided flexible coil RT setup and the standard setup for diagnostic radiology. The occurrence of motion artifacts was quantified. To develop magnetic resonance imaging (MRI) protocols, we formulated site- and disease-specific clinical objectives. RESULTS: Our novel setup showed mean SNR of 163 ± 28 anteriorly, 104 ± 23 centrally, and 78 ± 14 posteriorly compared to 84 ± 8 and 102 ± 22 anteriorly, 68 ± 6 and 95 ± 20 centrally, and 56 ± 7 and 119 ± 23 posteriorly for the vendor-provided and diagnostic setup, respectively. All differences were significant (p > 0.05). Image quality of our novel setup was judged suitable for contouring by expert-based assessment. Motion artifacts were found in 8/60 patients in the diagnostic setup, whereas none were found for patients in the RT setup. Site-specific core protocols were designed to minimize distortions while optimizing tissue contrast and 3D resolution according to indication-specific objectives. CONCLUSION: We present a novel setup for high-quality imaging in treatment position that allows use of several immobilization systems enabling MR-only workflows, which could reduce unnecessary dose and registration inaccuracies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00066-020-01703-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-78927402021-03-03 Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position Mengling, Veit Bert, Christoph Perrin, Rosalind Masitho, Siti Weissmann, Thomas Mansoorian, Sina Siavooshhaghighi, Hadi Janka, Rolf Doussin, Sylvain Habatsch, Melanie Fietkau, Rainer Putz, Florian Strahlenther Onkol Original Article PURPOSE: To share our experiences in implementing a dedicated magnetic resonance (MR) scanner for radiotherapy (RT) treatment planning using a novel coil setup for brain imaging in treatment position as well as to present developed core protocols with sequences specifically tuned for brain and prostate RT treatment planning. MATERIALS AND METHODS: Our novel setup consists of two large 18-channel flexible coils and a specifically designed wooden mask holder mounted on a flat tabletop overlay, which allows patients to be measured in treatment position with mask immobilization. The signal-to-noise ratio (SNR) of this setup was compared to the vendor-provided flexible coil RT setup and the standard setup for diagnostic radiology. The occurrence of motion artifacts was quantified. To develop magnetic resonance imaging (MRI) protocols, we formulated site- and disease-specific clinical objectives. RESULTS: Our novel setup showed mean SNR of 163 ± 28 anteriorly, 104 ± 23 centrally, and 78 ± 14 posteriorly compared to 84 ± 8 and 102 ± 22 anteriorly, 68 ± 6 and 95 ± 20 centrally, and 56 ± 7 and 119 ± 23 posteriorly for the vendor-provided and diagnostic setup, respectively. All differences were significant (p > 0.05). Image quality of our novel setup was judged suitable for contouring by expert-based assessment. Motion artifacts were found in 8/60 patients in the diagnostic setup, whereas none were found for patients in the RT setup. Site-specific core protocols were designed to minimize distortions while optimizing tissue contrast and 3D resolution according to indication-specific objectives. CONCLUSION: We present a novel setup for high-quality imaging in treatment position that allows use of several immobilization systems enabling MR-only workflows, which could reduce unnecessary dose and registration inaccuracies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00066-020-01703-y) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2020-10-25 2021 /pmc/articles/PMC7892740/ /pubmed/33103231 http://dx.doi.org/10.1007/s00066-020-01703-y Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Article
Mengling, Veit
Bert, Christoph
Perrin, Rosalind
Masitho, Siti
Weissmann, Thomas
Mansoorian, Sina
Siavooshhaghighi, Hadi
Janka, Rolf
Doussin, Sylvain
Habatsch, Melanie
Fietkau, Rainer
Putz, Florian
Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
title Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
title_full Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
title_fullStr Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
title_full_unstemmed Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
title_short Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
title_sort implementation of a dedicated 1.5 t mr scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892740/
https://www.ncbi.nlm.nih.gov/pubmed/33103231
http://dx.doi.org/10.1007/s00066-020-01703-y
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