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CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes

To identify markers in the CSF of multiple sclerosis (MS) subtypes, we used a two-step proteomic approach: (i) Discovery proteomics compared 169 pooled CSF from MS subtypes and inflammatory/degenerative CNS diseases (NMO spectrum and Alzheimer disease) and healthy controls. (ii) Next, 299 proteins s...

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Detalles Bibliográficos
Autores principales: Elkjaer, Maria L., Nawrocki, Arkadiusz, Kacprowski, Tim, Lassen, Pernille, Simonsen, Anja Hviid, Marignier, Romain, Sejbaek, Tobias, Nielsen, Helle H., Wermuth, Lene, Rashid, Alyaa Yakut, Høgh, Peter, Sellebjerg, Finn, Reynolds, Richard, Baumbach, Jan, Larsen, Martin R., Illes, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892884/
https://www.ncbi.nlm.nih.gov/pubmed/33603109
http://dx.doi.org/10.1038/s41598-021-83591-5