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A review on the advancements in the development of vaccines to combat coronavirus disease 2019
Coronavirus disease 2019 (COVID-19), the deadly disease caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a global pandemic that has severely affected lives and economies around the globe. The spread of this virus will be very difficult to contain if no vaccine is ready for i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Vaccine Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892947/ https://www.ncbi.nlm.nih.gov/pubmed/33628749 http://dx.doi.org/10.7774/cevr.2021.10.1.6 |
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author | Onyeaka, Helen Al-Sharify, Zainab T. Ghadhban, Maryam Yousif Al-Najjar, Shahad Z. |
author_facet | Onyeaka, Helen Al-Sharify, Zainab T. Ghadhban, Maryam Yousif Al-Najjar, Shahad Z. |
author_sort | Onyeaka, Helen |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19), the deadly disease caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a global pandemic that has severely affected lives and economies around the globe. The spread of this virus will be very difficult to contain if no vaccine is ready for implementation. This is because of the high human-to-human transmission rate of this virus and the fact that the virus is in the community spread stage. As of 31st August 2020, 25.3 million individuals have been affected by this deadly virus resulting in about 850,673 deaths. To combat the spread of COVID-19, more than 100 applicant immunizations are being developed around the world. Among them, eight have begun or will be soon beginning preliminary clinical trials. This paper provides a review of the current developments of potential COVID-19 vaccines around the world. It specifically discusses the recombinant vaccine produced by the University of Oxford and AstraZeneca (Cambridge, UK), the use of novel self-amplifying RNA technique to create a vaccine and the progress made by UNAID (US National Institute of Allergy and Infectious Diseases) and World Health Organization (WHO). Furthermore, this review demonstrates the pharmaceutical prophylaxis and treatment protocols for COVID-19 by analysing the documentation set up by the WHO for up to date data with respect to the novel coronavirus of 2019–2020. |
format | Online Article Text |
id | pubmed-7892947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Vaccine Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-78929472021-02-23 A review on the advancements in the development of vaccines to combat coronavirus disease 2019 Onyeaka, Helen Al-Sharify, Zainab T. Ghadhban, Maryam Yousif Al-Najjar, Shahad Z. Clin Exp Vaccine Res Review Article Coronavirus disease 2019 (COVID-19), the deadly disease caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a global pandemic that has severely affected lives and economies around the globe. The spread of this virus will be very difficult to contain if no vaccine is ready for implementation. This is because of the high human-to-human transmission rate of this virus and the fact that the virus is in the community spread stage. As of 31st August 2020, 25.3 million individuals have been affected by this deadly virus resulting in about 850,673 deaths. To combat the spread of COVID-19, more than 100 applicant immunizations are being developed around the world. Among them, eight have begun or will be soon beginning preliminary clinical trials. This paper provides a review of the current developments of potential COVID-19 vaccines around the world. It specifically discusses the recombinant vaccine produced by the University of Oxford and AstraZeneca (Cambridge, UK), the use of novel self-amplifying RNA technique to create a vaccine and the progress made by UNAID (US National Institute of Allergy and Infectious Diseases) and World Health Organization (WHO). Furthermore, this review demonstrates the pharmaceutical prophylaxis and treatment protocols for COVID-19 by analysing the documentation set up by the WHO for up to date data with respect to the novel coronavirus of 2019–2020. The Korean Vaccine Society 2021-01 2021-01-31 /pmc/articles/PMC7892947/ /pubmed/33628749 http://dx.doi.org/10.7774/cevr.2021.10.1.6 Text en © Korean Vaccine Society. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Onyeaka, Helen Al-Sharify, Zainab T. Ghadhban, Maryam Yousif Al-Najjar, Shahad Z. A review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
title | A review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
title_full | A review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
title_fullStr | A review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
title_full_unstemmed | A review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
title_short | A review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
title_sort | review on the advancements in the development of vaccines to combat coronavirus disease 2019 |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892947/ https://www.ncbi.nlm.nih.gov/pubmed/33628749 http://dx.doi.org/10.7774/cevr.2021.10.1.6 |
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