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ClC-5 Downregulation Induces Osteosarcoma Cell Apoptosis by Promoting Bax and tBid Complex Formation
Osteosarcoma is the most common malignant bone tumor. Chloride (Cl(−)) channels-mediated Cl(−) movement plays an important role in regulating the functions of various cancer cells, but its role in osteosarcoma remains unclear. In this study, we found that ClC-5 was increased in osteosarcoma tissues...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892965/ https://www.ncbi.nlm.nih.gov/pubmed/33614474 http://dx.doi.org/10.3389/fonc.2020.556908 |