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Global DNA methylation levels in white blood cells of patients with chronic heroin use disorder. A prospective study

BACKGROUND: Increasing scientific evidence shows the significant role of epigenetic mechanisms in drug use disorder, abstinence and relapse. Studies on human subjects are limited compared to those on animals, for various reasons such as poly-substance abuse, high drop-out rate and technical difficul...

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Detalles Bibliográficos
Autores principales: Fragou, Domniki, Chao, Mu-Rong, Hu, Chiung-Wen, Nikolaou, Kakia, Kovatsi, Leda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892979/
https://www.ncbi.nlm.nih.gov/pubmed/33643851
http://dx.doi.org/10.1016/j.toxrep.2021.02.006