Cargando…
Protease OMA1 modulates mitochondrial bioenergetics and ultrastructure through dynamic association with MICOS complex
Remodeling of mitochondrial ultrastructure is a process that is critical for organelle physiology and apoptosis. Although the key players in this process—mitochondrial contact site and cristae junction organizing system (MICOS) and Optic Atrophy 1 (OPA1)—have been characterized, the mechanisms behin...
Autores principales: | Viana, Martonio Ponte, Levytskyy, Roman M., Anand, Ruchika, Reichert, Andreas S., Khalimonchuk, Oleh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892988/ https://www.ncbi.nlm.nih.gov/pubmed/33644718 http://dx.doi.org/10.1016/j.isci.2021.102119 |
Ejemplares similares
-
Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells
por: Daverey, Amita, et al.
Publicado: (2019) -
Protocol for engineering and validating a synthetic mitochondrial intermembrane bridge in mammalian cells
por: Purohit, Gunjan, et al.
Publicado: (2022) -
Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability
por: Bohovych, Iryna, et al.
Publicado: (2015) -
Emerging Roles of the MICOS Complex in Cristae Dynamics and Biogenesis
por: Anand, Ruchika, et al.
Publicado: (2021) -
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
por: Anand, Ruchika, et al.
Publicado: (2014)