Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish

Conditional gene inactivation is a powerful tool to determine gene function when constitutive mutations result in detrimental effects. The most commonly used technique to achieve conditional gene inactivation employs the Cre/loxP system and its ability to delete DNA sequences flanked by two loxP sit...

Descripción completa

Detalles Bibliográficos
Autores principales: Hans, Stefan, Zöller, Daniela, Hammer, Juliane, Stucke, Johanna, Spieß, Sandra, Kesavan, Gokul, Kroehne, Volker, Eguiguren, Juan Sebastian, Ezhkova, Diana, Petzold, Andreas, Dahl, Andreas, Brand, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893016/
https://www.ncbi.nlm.nih.gov/pubmed/33602923
http://dx.doi.org/10.1038/s41467-021-21427-6

Ejemplares similares

Ejemplares similares