Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Mitochondrial fusion/fission dynamics plays a fundamental role in neuroprotection; however, there is still a severe lack of therapeutic targets for this biological process. Here, we found that the naturally derived small molecule echinacoside (ECH) significantly promotes mitochondrial fusion progres...

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Detalles Bibliográficos
Autores principales: Zeng, Ke-Wu, Wang, Jing-Kang, Wang, Li-Chao, Guo, Qiang, Liu, Ting-Ting, Wang, Fu-Jiang, Feng, Na, Zhang, Xiao-Wen, Liao, Li-Xi, Zhao, Mei-Mei, Liu, Dan, Jiang, Yong, Tu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893052/
https://www.ncbi.nlm.nih.gov/pubmed/33602894
http://dx.doi.org/10.1038/s41392-020-00447-6

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