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Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice

OBJECTIVE: Astrocytes are glial cells proposed as the main Sonic hedgehog (Shh)-responsive cells in the adult brain. Their roles in mediating Shh functions are still poorly understood. In the hypothalamus, astrocytes support neuronal circuits implicated in the regulation of energy metabolism. In thi...

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Detalles Bibliográficos
Autores principales: Tirou, Linda, Russo, Mariagiovanna, Faure, Helene, Pellegrino, Giuliana, Demongin, Clement, Daynac, Mathieu, Sharif, Ariane, Amosse, Jeremy, Le Lay, Soazig, Denis, Raphaël, Luquet, Serge, Taouis, Mohammed, Benomar, Yacir, Ruat, Martial
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893488/
https://www.ncbi.nlm.nih.gov/pubmed/33513436
http://dx.doi.org/10.1016/j.molmet.2021.101172