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Saikosaponin-d increases radiation-induced apoptosis of hepatoma cells by promoting autophagy via inhibiting mTOR phosphorylation

Objective: The aim of this study was to analyze the effects of saikosaponin-d (SSd) on autophagy activity and radiosensitivity of hepatoma cells, and to elucidate its related molecular mechanisms. Methods: The growth of SMMC-7721 and MHCC97L hepatoma cells were detected by clonal formation and survi...

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Detalles Bibliográficos
Autores principales: Wang, Baofeng, Min, Weili, Lin, Shuai, Song, Lingqin, Yang, Pengtao, Ma, Qingyong, Guo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893567/
https://www.ncbi.nlm.nih.gov/pubmed/33628104
http://dx.doi.org/10.7150/ijms.53024