Population differences in vaccine responses (POPVAC): scientific rationale and cross-cutting analyses for three linked, randomised controlled trials assessing the role, reversibility and mediators of immunomodulation by chronic infections in the tropics

INTRODUCTION: Vaccine-specific immune responses vary between populations and are often impaired in low income, rural settings. Drivers of these differences are not fully elucidated, hampering identification of strategies for optimising vaccine effectiveness. We hypothesise that urban–rural (and regi...

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Detalles Bibliográficos
Autores principales: Nkurunungi, Gyaviira, Zirimenya, Ludoviko, Natukunda, Agnes, Nassuuna, Jacent, Oduru, Gloria, Ninsiima, Caroline, Zziwa, Christopher, Akello, Florence, Kizindo, Robert, Akello, Mirriam, Kaleebu, Pontiano, Wajja, Anne, Luzze, Henry, Cose, Stephen, Webb, Emily, Elliott, Alison M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893603/
https://www.ncbi.nlm.nih.gov/pubmed/33593767
http://dx.doi.org/10.1136/bmjopen-2020-040425

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