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FBXW7 mediates high glucose-induced SREBP-1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation

Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and lipid metabolism abnormality serves a key role in the pathogenesis of DN. Sterol regulatory element-binding protein 1 (SREBP-1) overexpression mediates aberrant lipid accumulation in renal tubular cells of DN. However, the e...

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Detalles Bibliográficos
Autores principales:	Li, Lisha, Yang, Juxiang, Li, Fan, Gao, Fan, Zhu, Lin, Hao, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893693/ https://www.ncbi.nlm.nih.gov/pubmed/33537812 http://dx.doi.org/10.3892/mmr.2021.11872

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