Performance of model-based multifactor dimensionality reduction methods for epistasis detection by controlling population structure

BACKGROUND: In genome-wide association studies the extent and impact of confounding due to population structure have been well recognized. Inadequate handling of such confounding is likely to lead to spurious associations, hampering replication, and the identification of causal variants. Several str...

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Detalles Bibliográficos
Autores principales: Abegaz, Fentaw, Van Lishout, François, Mahachie John, Jestinah M., Chiachoompu, Kridsadakorn, Bhardwaj, Archana, Duroux, Diane, Gusareva, Elena S., Wei, Zhi, Hakonarson, Hakon, Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893746/
https://www.ncbi.nlm.nih.gov/pubmed/33608043
http://dx.doi.org/10.1186/s13040-021-00247-w

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