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Schistosoma japonicum cystatin suppresses osteoclastogenesis via manipulating the NF-κB signaling pathway

Abnormal osteoclastic activation and secretion of cysteine proteinases result in excessive bone resorption, which is one of the primary factors in the development of bone metabolic disorders, such as rheumatoid arthritis and osteoporosis. Mammalian cystatins have been demonstrated to restrain osteoc...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Wei, Bangguo, Xu, Panpan, Tang, Huadong, Yang, Langlang, Wang, Yuhang, Fu, Yingxiao, Yang, Xiaodi, Mao, Yingji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893784/
https://www.ncbi.nlm.nih.gov/pubmed/33576450
http://dx.doi.org/10.3892/mmr.2021.11912