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A systems-based method to repurpose marketed therapeutics for antiviral use: a SARS-CoV-2 case study
This study describes two complementary methods that use network-based and sequence similarity tools to identify drug repurposing opportunities predicted to modulate viral proteins. This approach could be rapidly adapted to new and emerging viruses. The first method built and studied a virus–host–phy...
Autores principales: | Wang, Mengran, Withers, Johanna B, Ricchiuto, Piero, Voitalov, Ivan, McAnally, Michael, Sanchez, Helia N, Saleh, Alif, Akmaev, Viatcheslav R, Ghiassian, Susan Dina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893815/ https://www.ncbi.nlm.nih.gov/pubmed/33593923 http://dx.doi.org/10.26508/lsa.202000904 |
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