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Optimization of scleroglucan production by Sclerotium rolfsii by lowering pH during fermentation via oxalate metabolic pathway manipulation using CRISPR/Cas9

BACKGROUND: Sclerotium rolfsii is a potent producer of many secondary metabolites, one of which like scleroglucan is an exopolysaccharide (EPS) appreciated as a multipurpose compound applicable in many industrial fields. RESULTS: Aspartate transaminase (AAT1) catalyzes the interconversion of asparta...

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Detalles Bibliográficos
Autores principales:	Bai, Tianlong, Wang, Teng, Li, Yan, Gao, Na L., Zhang, Lixin, Chen, Wei-Hua, Yin, Xiushan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893912/ https://www.ncbi.nlm.nih.gov/pubmed/33602329 http://dx.doi.org/10.1186/s40694-021-00108-5

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