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The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea
BACKGROUND: Weight fluctuation (WF) is highly prevalent in parallel with the high prevalence of intentional or unintentional dieting. The health risks of frequent WF for metabolic syndrome (MS) have become a public health concern, especially for health care providers who supervise dieting as an inte...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893930/ https://www.ncbi.nlm.nih.gov/pubmed/33602291 http://dx.doi.org/10.1186/s13690-021-00539-x |
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author | Chin, Young Ran So, Eun Sun |
author_facet | Chin, Young Ran So, Eun Sun |
author_sort | Chin, Young Ran |
collection | PubMed |
description | BACKGROUND: Weight fluctuation (WF) is highly prevalent in parallel with the high prevalence of intentional or unintentional dieting. The health risks of frequent WF for metabolic syndrome (MS) have become a public health concern, especially for health care providers who supervise dieting as an intervention to prevent obesity-related morbidity or to improve health, as well as for the general population for whom dieting is of interest. The aim of this study was to investigate the long-term effect of WF on the risk of MS in Koreans. METHODS: This study analyzed secondary data from the Korean Genome and Epidemiology Study, a 16-year prospective cohort study, on 8150 individuals using time-dependent Cox regression. RESULTS: WF did not increase the risk of MS in either normal-weight or obese subjects. In an analysis of the components of MS, greater WF significantly increased the risk of abdominal obesity (HR = 1.05, 95% CI = 1.02–1.07, p < 0.001) in normal-weight individuals. However, WF did not increase the risk of hyperglycemia, low high-density lipoprotein cholesterol levels, elevated blood pressure, or raised fasting glucose in normal-weight individuals, and it did not influence any of the components of MS in obese individuals. CONCLUSION: Since WF was found to be a risk factor for abdominal obesity, which is the most reliable predictor of MS, it should be considered when addressing weight control. Further studies on cut-off points for the degree of weight loss in a certain period need to be conducted to help clinicians provide guidance on appropriate weight control. |
format | Online Article Text |
id | pubmed-7893930 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-78939302021-02-22 The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea Chin, Young Ran So, Eun Sun Arch Public Health Research BACKGROUND: Weight fluctuation (WF) is highly prevalent in parallel with the high prevalence of intentional or unintentional dieting. The health risks of frequent WF for metabolic syndrome (MS) have become a public health concern, especially for health care providers who supervise dieting as an intervention to prevent obesity-related morbidity or to improve health, as well as for the general population for whom dieting is of interest. The aim of this study was to investigate the long-term effect of WF on the risk of MS in Koreans. METHODS: This study analyzed secondary data from the Korean Genome and Epidemiology Study, a 16-year prospective cohort study, on 8150 individuals using time-dependent Cox regression. RESULTS: WF did not increase the risk of MS in either normal-weight or obese subjects. In an analysis of the components of MS, greater WF significantly increased the risk of abdominal obesity (HR = 1.05, 95% CI = 1.02–1.07, p < 0.001) in normal-weight individuals. However, WF did not increase the risk of hyperglycemia, low high-density lipoprotein cholesterol levels, elevated blood pressure, or raised fasting glucose in normal-weight individuals, and it did not influence any of the components of MS in obese individuals. CONCLUSION: Since WF was found to be a risk factor for abdominal obesity, which is the most reliable predictor of MS, it should be considered when addressing weight control. Further studies on cut-off points for the degree of weight loss in a certain period need to be conducted to help clinicians provide guidance on appropriate weight control. BioMed Central 2021-02-18 /pmc/articles/PMC7893930/ /pubmed/33602291 http://dx.doi.org/10.1186/s13690-021-00539-x Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Chin, Young Ran So, Eun Sun The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea |
title | The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea |
title_full | The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea |
title_fullStr | The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea |
title_full_unstemmed | The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea |
title_short | The effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in South Korea |
title_sort | effects of weight fluctuation on the components of metabolic syndrome: a 16-year prospective cohort study in south korea |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893930/ https://www.ncbi.nlm.nih.gov/pubmed/33602291 http://dx.doi.org/10.1186/s13690-021-00539-x |
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