PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite

BACKGROUND: The airway epithelial barrier function is disrupted in the airways of asthmatic patients. Abnormal mitochondrial biogenesis is reportedly involved in the pathogenesis of asthma. However, the role of mitochondrial biogenesis in the airway barrier dysfunction has not been elucidated yet. T...

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Detalles Bibliográficos
Autores principales: Saito, Tsutomu, Ichikawa, Tomohiro, Numakura, Tadahisa, Yamada, Mitsuhiro, Koarai, Akira, Fujino, Naoya, Murakami, Koji, Yamanaka, Shun, Sasaki, Yusaku, Kyogoku, Yorihiko, Itakura, Koji, Sano, Hirohito, Takita, Katsuya, Tanaka, Rie, Tamada, Tsutomu, Ichinose, Masakazu, Sugiura, Hisatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893966/
https://www.ncbi.nlm.nih.gov/pubmed/33607992
http://dx.doi.org/10.1186/s12931-021-01663-6

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