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ECT2 promotes lung adenocarcinoma progression through extracellular matrix dynamics and focal adhesion signaling

Lung adenocarcinoma (LAC) is the most prevalent form of lung cancer. Epithelial cell transforming sequence 2 (ECT2) is a guanine nucleotide exchange factor that has been implicated in oncogenic and malignant phenotypes of LAC. Here, we identified an oncogenic role of ECT2 in the extracellular matrix...

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Detalles Bibliográficos
Autores principales: Kosibaty, Zeinab, Murata, Yoshihiko, Minami, Yuko, Noguchi, Masayuki, Sakamoto, Noriaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893990/
https://www.ncbi.nlm.nih.gov/pubmed/33215807
http://dx.doi.org/10.1111/cas.14743

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