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Prospective evaluation and refinement of an S‐1 dosage formula based on renal function for clinical application

In patients with impaired renal function, S‐1–related toxicities increase due to higher exposure of 5‐fluorouracil (5‐FU). Our previous pharmacokinetic study in 16 cancer patients with various renal functions developed an S‐1 dosage formula based on individual creatinine clearance (CLcr) and body su...

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Detalles Bibliográficos
Autores principales:	Takeuchi, Masashi, Imamura, Chiyo K., Booka, Eisuke, Takeuchi, Hiroya, Mizukami, Takuro, Kawakami, Takeshi, Funakoshi, Taro, Wakuda, Kazushige, Aoki, Yu, Hamamoto, Yasuo, Kitago, Minoru, Kawakubo, Hirofumi, Boku, Narikazu, Tanigawara, Yusuke, Kitagawa, Yuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894007/ https://www.ncbi.nlm.nih.gov/pubmed/33277781 http://dx.doi.org/10.1111/cas.14758

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