The actin-regulatory protein Hem-1 is essential for alveolar macrophage development

Hematopoietic protein-1 (Hem-1) is a hematopoietic cell–specific actin-regulatory protein. Loss-of-function (LOF) variants in the NCKAP1L gene encoding Hem-1 have recently been found to result in primary immunodeficiency disease (PID) in humans, characterized by recurring respiratory infections, ast...

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Detalles Bibliográficos
Autores principales: Suwankitwat, Nutthakarn, Libby, Stephen, Liggitt, H. Denny, Avalos, Alan, Ruddell, Alanna, Rosch, Jason W., Park, Heon, Iritani, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894047/
https://www.ncbi.nlm.nih.gov/pubmed/33600594
http://dx.doi.org/10.1084/jem.20200472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894047/
https://www.ncbi.nlm.nih.gov/pubmed/33600594
http://dx.doi.org/10.1084/jem.20200472

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