Cargando…

The actin-regulatory protein Hem-1 is essential for alveolar macrophage development

Hematopoietic protein-1 (Hem-1) is a hematopoietic cell–specific actin-regulatory protein. Loss-of-function (LOF) variants in the NCKAP1L gene encoding Hem-1 have recently been found to result in primary immunodeficiency disease (PID) in humans, characterized by recurring respiratory infections, ast...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suwankitwat, Nutthakarn, Libby, Stephen, Liggitt, H. Denny, Avalos, Alan, Ruddell, Alanna, Rosch, Jason W., Park, Heon, Iritani, Brian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894047/ https://www.ncbi.nlm.nih.gov/pubmed/33600594 http://dx.doi.org/10.1084/jem.20200472

Ejemplares similares

Hem-1 regulates protective humoral immunity and limits autoantibody production in a B cell–specific manner
por: Avalos, Alan, et al.
Publicado: (2022)

A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
por: Park, Heon, et al.
Publicado: (2008)

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
por: Cohen, Jarish N., et al.
Publicado: (2010)

Idiopathic Pulmonary Alveolar Proteinosis as an Autoimmune Disease with Neutralizing Antibody against Granulocyte/Macrophage Colony-Stimulating Factor
por: Kitamura, Takayuki, et al.
Publicado: (1999)

Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b
por: Föger, Niko, et al.
Publicado: (2011)

Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth
por: Ganti, Sheila N., et al.
Publicado: (2015)

The interactions and essential effects of intrinsic insulin-like growth factor-I on Leishmania (Leishmania) major growth within macrophages
por: Reis, L C, et al.
Publicado: (2013)

REGULATION OF LYMPHOCYTE RESPONSES IN VITRO : I. REGULATORY EFFECT OF MACROPHAGES AND THYMUS-DEPENDENT (T) CELLS ON THE RESPONSE OF THYMUS-INDEPENDENT (B) LYMPHOCYTES TO ENDOTOXIN
por: Yoshinaga, Masaru, et al.
Publicado: (1972)

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25(+)Cd4(+) Regulatory Cells That Control Intestinal Inflammation
por: Read, Simon, et al.
Publicado: (2000)

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA
por: Suzuki, Takuji, et al.
Publicado: (2008)

Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling
por: Campi, Gabriele, et al.
Publicado: (2005)

Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1
por: Sakata, Daiji, et al.
Publicado: (2007)

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo
por: Yadav, Mahesh, et al.
Publicado: (2012)

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRα gene in the X chromosome pseudoautosomal region 1
por: Martinez-Moczygemba, Margarita, et al.
Publicado: (2008)

Identification of Regulatory T Cells in Tolerated Allografts
por: Graca, Luis, et al.
Publicado: (2002)

RANKL-induced DC-STAMP Is Essential for Osteoclastogenesis
por: Kukita, Toshio, et al.
Publicado: (2004)

Vav1 Phosphorylation Is Induced by β2 Integrin Engagement on Natural Killer Cells Upstream of Actin Cytoskeleton and Lipid Raft Reorganization
por: Riteau, Béatrice, et al.
Publicado: (2003)

Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes
por: Westerberg, Lisa S., et al.
Publicado: (2010)

Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis
por: Weiner, Orion D, et al.
Publicado: (2006)

Periostin is essential for cardiac healingafter acute myocardial infarction
por: Shimazaki, Masashi, et al.
Publicado: (2008)

An Essential Role for Thymic Mesenchyme in Early T Cell Development
por: Suniara, Ravinder K., et al.
Publicado: (2000)

CD80 Costimulation Is Essential for the Induction of Airway Eosinophilia
por: Harris, Nicola, et al.
Publicado: (1997)

METABOLIC AND FUNCTIONAL STUDIES ON ACTIVATED MOUSE MACROPHAGES
por: Stubbs, Marion, et al.
Publicado: (1973)

Peripheral Autoantigen Induces Regulatory T Cells that Prevent Autoimmunity
por: Seddon, Benedict, et al.
Publicado: (1999)

Secreted Lymphotoxin-α Is Essential for the Control of an Intracellular Bacterial Infection
por: Roach, Daniel R., et al.
Publicado: (2001)

The Paf oncogene is essential for hematopoietic stem cell function and development
por: Amrani, Yacine M., et al.
Publicado: (2011)

Inflammasome recognition of influenza virus is essential for adaptive immune responses
por: Ichinohe, Takeshi, et al.
Publicado: (2009)

Dynamic Interactions of Macrophages with T Cells during Antigen Presentation
por: Underhill, David M., et al.
Publicado: (1999)

Progressive replacement of embryo-derived cardiac macrophages with age
por: Molawi, Kaaweh, et al.
Publicado: (2014)

Imaging resident and recruited macrophage contribution to Wallerian degeneration
por: Boissonnas, Alexandre, et al.
Publicado: (2020)

Foxp3(+) regulatory T cells maintain immune homeostasis in the skin
por: Dudda, Jan C., et al.
Publicado: (2008)

OX40 is required for regulatory T cell–mediated control of colitis
por: Griseri, Thibault, et al.
Publicado: (2010)

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
por: Darrasse-Jèze, Guillaume, et al.
Publicado: (2009)

Human CD4(+)CD25(+) Regulatory, Contact-dependent T Cells Induce Interleukin 10–producing, Contact-independent Type 1-like Regulatory T Cells
por: Dieckmann, Detlef, et al.
Publicado: (2002)

Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation
por: Munder, Markus, et al.
Publicado: (1998)

The transcription factor XBP-1 is essential for the development and survival of dendritic cells
por: Iwakoshi, Neal N., et al.
Publicado: (2007)

Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence
por: Schrettl, Markus, et al.
Publicado: (2004)

Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
por: Nikitopoulou, Ioanna, et al.
Publicado: (2012)

Phospholipase Cγ1 is essential for T cell development, activation, and tolerance
por: Fu, Guoping, et al.
Publicado: (2010)

Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development
por: Choi, Jin Huk, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s751mjlnk2jb66ub4tjmf3cat6