Transmissibility of asymptomatic COVID-19: Data from Japanese clusters

BACKGROUND: The epidemiological importance of asymptomatic individuals who would never develop illness, compared to those who eventually develop symptoms, has yet to be fully clarified. METHODS: The very first cluster data in Tokyo and Kanagawa (n = 36) were analyzed. Movement of all close contact w...

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Detalles Bibliográficos
Autores principales: Nakajo, Ko, Nishiura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894083/
https://www.ncbi.nlm.nih.gov/pubmed/33618004
http://dx.doi.org/10.1016/j.ijid.2021.02.065
Descripción
Sumario:BACKGROUND: The epidemiological importance of asymptomatic individuals who would never develop illness, compared to those who eventually develop symptoms, has yet to be fully clarified. METHODS: The very first cluster data in Tokyo and Kanagawa (n = 36) were analyzed. Movement of all close contact was restricted for 14 days and they underwent laboratory testing with polymerase chain reaction. The reproduction numbers of symptomatic and asymptomatic cases were estimated. RESULTS: The reproduction number for symptomatic cases was estimated to be 1.2 (95% confidence interval (CI): 0.5–2.9). The relative infectiousness of asymptomatically infected cases was estimated to be 0.27 (95% CI: 0.03–0.81) of symptomatic cases. CONCLUSION: The relative transmissibility of asymptomatic cases is limited. Observing clusters starting with symptomatic transmission might be sufficient for the control.

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