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Dynamics of thymus function and T cell receptor repertoire breadth in health and disease
T cell recognition of unknown antigens relies on the tremendous diversity of the T cell receptor (TCR) repertoire; generation of which can only occur in the thymus. TCR repertoire breadth is thus critical for not only coordinating the adaptive response against pathogens but also for mounting a respo...
Autores principales: | Granadier, David, Iovino, Lorenzo, Kinsella, Sinéad, Dudakov, Jarrod A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894242/ https://www.ncbi.nlm.nih.gov/pubmed/33608819 http://dx.doi.org/10.1007/s00281-021-00840-5 |
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