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Tuning the binding interface between Machupo virus glycoprotein and human transferrin receptor

Machupo virus, known to cause hemorrhagic fevers, enters human cells via binding with its envelope glycoprotein to transferrin receptor 1 (TfR). Similarly, the receptor interactions have been explored in biotechnological applications as a molecular system to ferry therapeutics across the cellular me...

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Detalles Bibliográficos
Autores principales: Sjöström, Dick J, Lundgren, Anneli, Garforth, Scott J, Bjelic, Sinisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894301/
https://www.ncbi.nlm.nih.gov/pubmed/33068039
http://dx.doi.org/10.1002/prot.26016

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